S2 - Organometallic catalysis

Organometallic catalysis is a cornerstone discipline in synthetic chemistry that harnesses transition metal complexes featuring metal-carbon bonds to accelerate and control organic transformations with remarkable efficiency and selectivity. It relies on fundamental mechanisms like oxidative addition, reductive elimination, migratory insertion, and β-hydride elimination, enabling processes such as cross-coupling (e.g., Suzuki, Heck), hydrogenation, olefin metathesis, and C-H activation under mild conditions. This field bridges homogeneous and heterogeneous catalysis, powering industrial-scale production of pharmaceuticals, polymers, and fine chemicals while inspiring ongoing innovations in asymmetric synthesis and sustainable methodologies.