Scientific Publications

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Abstract

A general synthesis for the preparation of chiral N-N′ substituted 1,2,5-thiadiazolidine 1,1-dioxides has been developed beginning with proteogenic amino acid, sulfuryl chloride, and dibromoethane. The selected chemistry and spectral properties of these compounds are examined. Overall, routes described are applicable to the synthesis of a variety of constrained dipeptidal sulfamides representing novel peptidomimetic scaffolds.


BibTex

@article{uniusa349,
    title={Cyclosulfamides as constraint dipeptides: the synthesis and structure of chiral substituted1,2,5-thiadiazolidine 1,1-dioxyde : Evalution of the toxicity.},
    author={Amel BENDJEDDOU, Djebbar, H, Berredjem, M, Hattab, Z, Regainia, Z and Aouf, N.E},
    journal={Phosphorus, Sulfur and Silicon}
    year={2006},
    volume={181},
    number={6},
    pages={1351-1362},
    publisher={}
}